Document Detail

[Acute pulmonary embolism].
MedLine Citation:
PMID:  20824603     Owner:  NLM     Status:  MEDLINE    
Acute pulmonary embolism (APE) presents with a broad clinical spectrum ranging from an even asymptomatic course to sudden cardiac death. Because APE is potentially life-threatening every suspicion of APE has to be clarified promptly by validated diagnostic algorithms. On the basis of the patients haemodynamic instability high-risk APE and non-high-risk APE is differentiated. Based on the presence of shock or hypotension every patient with suspicion of APE should promptly be stratified as high-risk APE or non-high-risk APE. There is a considerable difference in the diagnostic and therapeutic algorithms between high-risk and non-high-risk APE. In suspicion of high-risk APE the patients require immediate diagnosis by multidetector CT or echocardiography and immediate recanalization of the occluded pulmonary arteries by thrombolysis or embolectomy. In haemodynamically stable patients sequential diagnostic workup and prompt therapeutic anticoagulation is recommended.
S Braun; J Beyer-Westendorf; I Platzek; G Höffken; M Halank
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Publication Detail:
Type:  English Abstract; Journal Article     Date:  2010-09-07
Journal Detail:
Title:  Deutsche medizinische Wochenschrift (1946)     Volume:  135     ISSN:  1439-4413     ISO Abbreviation:  Dtsch. Med. Wochenschr.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-08     Completed Date:  2010-10-27     Revised Date:  2010-11-22    
Medline Journal Info:
Nlm Unique ID:  0006723     Medline TA:  Dtsch Med Wochenschr     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  1803-14; quiz 1814-8     Citation Subset:  IM    
Medizinische Klinik I - Pneumologie, Universitätsklinikum Carl-Gustav-Carus, Dresden, Germany.
Vernacular Title:
Die akute Lungenembolie.
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MeSH Terms
Acute Disease
Diagnosis, Differential
Enoxaparin / therapeutic use
Fibrinolytic Agents / therapeutic use
Heparin / therapeutic use
Heparin, Low-Molecular-Weight / therapeutic use
Pulmonary Embolism / diagnosis*,  drug therapy,  physiopathology,  surgery*
Risk Assessment
Risk Factors
Tomography, X-Ray Computed
Reg. No./Substance:
0/Enoxaparin; 0/Fibrinolytic Agents; 0/Heparin, Low-Molecular-Weight; 0/tinzaparin; 9005-49-6/Heparin
Erratum In:
Dtsch Med Wochenschr. 2010 Nov;135(44):2208

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