Document Detail

Acute pulmonary embolism in childhood.
MedLine Citation:
PMID:  15992866     Owner:  NLM     Status:  MEDLINE    
Pulmonary embolism is an uncommon, but potentially fatal disease in children. Most children with pulmonary embolism have underlying clinical conditions, of which the presence of a central venous catheter is the most frequent. The clinical presentation is often subtle, or masked by the underlying clinical condition. Diagnostic as well as therapeutic strategies for pulmonary embolism in children are mostly extrapolated from studies in adults. Pulmonary angiography is still the gold standard in diagnosing pulmonary embolism, but several other radiographic tests can be used to diagnose pulmonary embolism, including ventilation-perfusion lung scanning, helical computed tomography, magnetic resonance imaging and echocardiography. The choice of treatment depends on the clinical presentation of the patient. Anticoagulation is the mainstay of therapy for children with pulmonary embolism. However, thrombolytic therapy can be considered for patients with hemodynamic instability. The outcome of pediatric pulmonary embolism is uncertain and needs to be studied.
C Heleen Van Ommen; Marjolein Peters
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Publication Detail:
Type:  Journal Article; Review     Date:  2005-06-29
Journal Detail:
Title:  Thrombosis research     Volume:  118     ISSN:  0049-3848     ISO Abbreviation:  Thromb. Res.     Publication Date:  2006  
Date Detail:
Created Date:  2006-05-19     Completed Date:  2006-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326377     Medline TA:  Thromb Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  13-25     Citation Subset:  IM    
Department of Pediatric Hematology, Emma Children's Hospital AMC, PO Box 22700, 1100 DE Amsterdam, The Netherlands.
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MeSH Terms
Acute Disease
Anticoagulants / therapeutic use
Diagnostic Imaging
Pulmonary Embolism / diagnosis*,  therapy*
Reg. No./Substance:

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