Document Detail

Acute psychosis during the postictal period in a patient with idiopathic generalized epilepsy: Postictal psychosis or aggravation of schizophrenia? A case report and review of the literature.
MedLine Citation:
PMID:  22652424     Owner:  NLM     Status:  Publisher    
Postictal psychoses are common comorbid conditions of temporal lobe epilepsy and are reported to be characterized by affective changes. However, postictal psychoses are rare among patients with idiopathic generalized epilepsy, and the causal relationship between postictal psychoses and idiopathic generalized epilepsy is unknown. Here, we report the case of a man who had idiopathic generalized epilepsy and experienced 4 episodes of schizophrenia-like interictal psychosis before the age of 41years. At the age of 56years, he experienced a generalized tonic-clonic seizure for the first time in 15years and developed psychotic symptoms on the next day. Notably, in addition to the schizophrenia-like symptoms, the patient experienced mania-like symptoms such as elated mood, grandiose delusions, agitation, and pressured speech during the last psychotic episode in the postictal period. It was suspected that postictal neuronal processes and a predisposition to endogenous psychosis both contributed to the psychopathology of this episode.
Eisuke Sakakibara; Takuji Nishida; Kazuyuki Sugishita; Seiichiro Jinde; Yushi Inoue; Kiyoto Kasai
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-5-29
Journal Detail:
Title:  Epilepsy & behavior : E&B     Volume:  -     ISSN:  1525-5069     ISO Abbreviation:  -     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-6-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100892858     Medline TA:  Epilepsy Behav     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Department of Psychiatry, National Center of Neurology and Psychiatry, National Center Hospital, Japan; Department of Neuropsychiatry, The University of Tokyo Hospital, Japan.
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