| Acute promyelocytic leukemia: an unusual cause showing prolonged disseminated intravascular coagulation after placental abruption. | |
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MedLine Citation:
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PMID: 17713776 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Disseminated intravascular coagulation (DIC) caused by placental abruption usually improves rapidly after prompt delivery and adequate anti-DIC treatment. CASE: A 30-year-old nulliparous woman suffered from placental abruption at the 25th week of pregnancy, and emergent cesarean section was done immediately. She exhibited DIC, which continued even after termination of the pregnancy and anti-DIC treatment. She also showed neutropenia. We closely observed her, and at the 58th day postpartum, blast cells appeared in the peripheral blood and she was diagnosed with acute promyelocytic leukemia (APL). Induction chemotherapy was done successfully. The close observation after delivery enabled us to make the prompt diagnosis/treatment, leading to the complete remission. CONCLUSION: APL should be added to the list of differential diagnosis when DIC persists even after prompt delivery and appropriate anti-DIC treatment after placental abruption. |
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Authors:
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Yukako Morimatsu; Shigeki Matsubara; Noriko Hirose; Akihide Ohkuchi; Akio Izumi; Katsutoshi Ozaki; Keiya Ozawa; Mitsuaki Suzuki |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2007-08-23 |
Journal Detail:
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Title: Archives of gynecology and obstetrics Volume: 277 ISSN: 0932-0067 ISO Abbreviation: Arch. Gynecol. Obstet. Publication Date: 2008 Mar |
Date Detail:
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Created Date: 2008-02-12 Completed Date: 2008-07-31 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710213 Medline TA: Arch Gynecol Obstet Country: Germany |
Other Details:
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Languages: eng Pagination: 267-70 Citation Subset: IM |
Affiliation:
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Department of Obstetrics and Gynecology, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abruptio Placentae
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etiology*,
surgery Adult Antineoplastic Agents / therapeutic use Cesarean Section Disseminated Intravascular Coagulation / etiology* Female Humans Leukemia, Promyelocytic, Acute / diagnosis*, drug therapy Neutropenia / etiology Pregnancy Pregnancy Complications, Neoplastic / diagnosis*, drug therapy |
| Chemical | |
Reg. No./Substance:
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0/Antineoplastic Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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