| Acute promyelocytic leukemia during pregnancy. | |
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MedLine Citation:
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PMID: 20447623 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To report our experience about a woman with acute promyelocytic leukemia (APL) during pregnancy. We focus on the obstetric treatment of our patient. DESIGN: Case report. SETTING: University Hospital. PATIENT(S): A 32-year-old-woman, gravida 2, para 1, at the 25th week of pregnancy with a diagnosis of APL. INTERVENTION(S): Multidisciplinary approach to the problem with the aim to ensure a good outcome for both the mother and the baby. MAIN OUTCOME MEASURE(S): Treatment of maternal malignancy and fetal outcome. RESULT(S): At discharge, after 2 months in hospital, the baby had no neurologic or sensitive deficiencies, and his general health was good. The mother is now undergoing the third and last consolidation step with good results, and APL is in remission. CONCLUSION(S): In cases of APL during the second and third trimesters, the modern chemotherapy associated with close monitoring of maternal and fetal well-being could ensure a good outcome for both the mother and the baby. |
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Authors:
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Laura Ganzitti; Giorgio Fachechi; Lorenza Driul; Diego Marchesoni |
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Publication Detail:
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Type: Case Reports; Journal Article Date: 2010-05-05 |
Journal Detail:
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Title: Fertility and sterility Volume: 94 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2010 Nov |
Date Detail:
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Created Date: 2010-10-27 Completed Date: 2010-12-08 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 2330.e5-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Clinic of Obstetrics and Gynaecology, University Hospital of Udine, Udine, Italy. ganzittilaura@live.it |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antineoplastic Combined Chemotherapy Protocols / therapeutic use Dexamethasone / administration & dosage Female Fetal Monitoring Humans Idarubicin / administration & dosage Infant, Newborn Interdisciplinary Communication Leukemia, Promyelocytic, Acute / diagnosis*, therapy Pregnancy Pregnancy Complications, Neoplastic / diagnosis*, therapy Pregnancy Trimester, Second Tretinoin / administration & dosage |
| Chemical | |
Reg. No./Substance:
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302-79-4/Tretinoin; 50-02-2/Dexamethasone; 58957-92-9/Idarubicin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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