Document Detail


Acute post-streptococcal glomerulonephritis associated with prolonged hypocomplementaemia.
MedLine Citation:
PMID:  18820103     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The case of a 6-year-old boy who presented with acute post-streptococcal glomerulonephritis is reported. C3 levels and complement alternative pathway activity remained low for at least 10 months after presentation, before returning to normal. There was no evidence of other renal disease. This case highlights that hypocomplementaemia in acute post-streptococcal glomerulonephritis may persist for several months, and that prolonged hypocomplementaemia does not exclude this diagnosis.
Authors:
D Payne; P Houtman; M Browning
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of clinical pathology     Volume:  61     ISSN:  1472-4146     ISO Abbreviation:  J. Clin. Pathol.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-09-29     Completed Date:  2008-10-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376601     Medline TA:  J Clin Pathol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1133-5     Citation Subset:  AIM; IM    
Affiliation:
Department of Immunology, Leicester Royal Infirmary, Leicester, UK. daniel.payne@uhl-tr.nhs.uk
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Child
Complement C3 / deficiency*
Complement Pathway, Alternative
Glomerulonephritis / immunology*,  microbiology*
Humans
Kidney Glomerulus / pathology
Male
Streptococcal Infections / complications*,  immunology
Streptococcus pyogenes*
Time
Chemical
Reg. No./Substance:
0/Complement C3

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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