| Acute plasma volume expansion alters cardiovascular but not thermal function during moderate intensity prolonged exercise. | |
| | |
MedLine Citation:
|
PMID: 10721816 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To investigate the hypothesis that the increase in plasma volume (PV) that typically occurs with training results in improved cardiovascular and thermal regulation during prolonged exercise, eight untrained males (V(O2)peak = 3.52 +/- 0.12 L x min(-1)) performed 90 min of cycle ergometry at 62% V(O2)peak before and after acute PV expansion. Subjects were infused with a PV-expanding solution (dextran (6%) or Pentaspan (10%)) equivalent to 6.7 mL x kg(-1) body mass (PVX) or acted as their own control (CON) in a randomized order. PVX resulted in a calculated 15.8% increase in resting PV, which relative to CON, was maintained throughout the exercise (P < 0.05). During PVX, heart rate was lower (P < 0.05) and stroke volume and cardiac output were higher (P < 0.05) during the exercise. Mean arterial pressure and total peripheral resistance, although altered by exercise (P < 0.05), were not different between the two conditions. Core temperature, which was progressively increased by the exercise (P < 0.01), was not affected by PVX. A similar decrease in body weight was observed between the conditions as a result of the exercise (P < 0.01). These results indicate that acute PVX alters cardiovascular performance without affecting the thermoregulatory response to prolonged cycle exercise. |
| | |
Authors:
|
B D Roy; H J Green; S M Grant; M A Tarnopolsky |
Related Documents
:
|
1575046 - Age-related changes of exercise-induced plasma catecholamines and neuropeptide y respon... 2676946 - Menstrual status and plasma vasopressin, renin activity, and aldosterone exercise respo... 1868676 - Increased suppression of exercise-induced increase in renin by propranolol in chinese s... 443066 - Fasting and prolonged exercise increase vasoactive intestinal polypeptide (vip) in plasma. 19489006 - Endogenous cannabinoid signaling is required for voluntary exercise-induced enhancement... 21283326 - Spinal claudication. |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Canadian journal of physiology and pharmacology Volume: 78 ISSN: 0008-4212 ISO Abbreviation: Can. J. Physiol. Pharmacol. Publication Date: 2000 Mar |
Date Detail:
|
Created Date: 2000-05-11 Completed Date: 2000-05-11 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0372712 Medline TA: Can J Physiol Pharmacol Country: CANADA |
Other Details:
|
Languages: eng Pagination: 244-50 Citation Subset: IM |
Affiliation:
|
Department of Kinesiology, University of Waterloo, ON, Canada. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Body Temperature Body Temperature Regulation* Cardiac Output Exercise* Heart Rate Hemodynamics* Humans Male Oxygen Consumption Plasma Volume* Stroke Volume |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Distribution of alpha1-adrenoceptor subtype proteins in different tissues of neonatal and adult rats...
Next Document: Vasodilation in human subcutaneous arteries induced by neuropeptide Y is mediated by neuropeptide Y ...