Document Detail

Acute phase proteins in "small for dates" babies. II. Haptoglobin, transferrin, alpha-1-feto protein, alpha-1-acid glycoprotein and caeruloplasmin levels.
MedLine Citation:
PMID:  1283808     Owner:  NLM     Status:  MEDLINE    
Haptoglobin, transferrin, alpha-1-feto-protein (AFP), alpha-1-acid glycoprotein (AAGP) and caeruloplasmin levels were estimated in 14 "small for dates" (SFD) and 31 "appropriate for dates" (AFD) babies by the single radial immunodiffusion method. The mean caeruloplasmin levels was observed to be significantly reduced in the SFD babies when compared with the AFD babies (t = 3.4582, P < 0.02). None of the other 4 acute phase proteins showed any significant differences in mean concentration between the SFD babies and the controls. The diminished caeruloplasmin levels observed in SFD babies agrees with previous reports in post-natal undernutrition. Our findings of no significant differences in the other 4 acute phase proteins between SFD and AFD babies are however at variance with previous observations of elevated levels of AFP, haptoglobin and AAGP and reduced levels of transferrin in malnourished infants.
L S Salimonu
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  African journal of medicine and medical sciences     Volume:  21     ISSN:  0309-3913     ISO Abbreviation:  Afr J Med Med Sci     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1993-03-15     Completed Date:  1993-03-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7801013     Medline TA:  Afr J Med Med Sci     Country:  NIGERIA    
Other Details:
Languages:  eng     Pagination:  55-9     Citation Subset:  IM; J    
Department of Chemical Pathology, University College Hospital, Ibadan, Nigeria.
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MeSH Terms
Ceruloplasmin / chemistry*
Fetal Blood / chemistry
Fetal Growth Retardation / blood,  epidemiology
Haptoglobins / chemistry*
Infant Nutrition Disorders / blood,  epidemiology
Infant, Newborn
Infant, Small for Gestational Age / blood*
Nigeria / epidemiology
Orosomucoid / chemistry*
Transferrin / chemistry*
alpha-Fetoproteins / chemistry*
Reg. No./Substance:
0/Haptoglobins; 0/Orosomucoid; 0/alpha-Fetoproteins; 11096-37-0/Transferrin; EC

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