| Acute parvovirus B19 infection mimicking myelodysplastic syndrome of the bone marrow. | |
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MedLine Citation:
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PMID: 1739758 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 36-year-old, previously healthy woman was referred to our institution with pancytopenia and splenomegaly for suspected acute leukemia. Bone marrow aspiration showed marked dysplastic changes, excess of blasts, and only spurious red blood cell precursors. Action was taken to prepare allogeneic bone marrow transplantation from an HLA identical sibling for myelodysplastic syndrome. Repeat cytological examination of the bone marrow revealed striking hyperplasia of the red cell line with presence of abnormal giant proerythroblasts. Acute parvovirus B19 infection was suspected and confirmed by detection of anti-B19 IgM and B19 DNA. The underlying disease for this transient aplastic crisis was a formerly unknown hereditary spherocytosis. |
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Authors:
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H Baurmann; T F Schwarz; J Oertel; S Serke; M Roggendorf; D Huhn |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Annals of hematology Volume: 64 ISSN: 0939-5555 ISO Abbreviation: Ann. Hematol. Publication Date: 1992 Jan |
Date Detail:
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Created Date: 1992-03-26 Completed Date: 1992-03-26 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 9107334 Medline TA: Ann Hematol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 43-5 Citation Subset: IM |
Affiliation:
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Abteilung für Innere Medizin mit Schwerpunkt Hämatologie und Onkologie, Universitätsklinikum Rudolf Virchow, Standort Charlottenburg, Freie Universität Berlin, FRG. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Bone Marrow / pathology Diagnosis, Differential Erythema Infectiosum / diagnosis* Female Humans Myelodysplastic Syndromes / diagnosis* |
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