Document Detail

Acute parotitis induced by trimethoprim/sulfamethoxazole.
MedLine Citation:
PMID:  21328218     Owner:  NLM     Status:  In-Data-Review    
Adverse drug reactions to the sulfonamide antibiotics are uncommon. When they do occur, they usually manifest as a rash or urticaria. Our review of the recent literature found that while sialadenitis is listed as a possible side effect of sulfonamide use, no actual case has ever been reported until now. We describe a case of acute bilateral parotitis that arose as a side effect of sulfonamide antibiotic treatment. We also examine the relevance of such pathology to the proposed mechanisms of sialadenitis, and we briefly discuss sulfonamide-induced pancreatitis. Lastly, we review the controversy over the possibility that some adverse drug reactions may be caused by cross-reactivity among different classes of sulfonamides.
Jayna S Patel; Edward D Scheiner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ear, nose, & throat journal     Volume:  90     ISSN:  1942-7522     ISO Abbreviation:  Ear Nose Throat J     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-02-17     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7701817     Medline TA:  Ear Nose Throat J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  E22-4     Citation Subset:  IM    
Department of Otolaryngology and Facial Plastic Surgery, Kennedy Memorial Hospitals-University Medical Center, 3101 Burrough's Mill Cir., Cherry Hill, NJ 08002, USA.
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