Document Detail

Acute pancreatitis secondary to pancreatic neuroendocrine tumours.
MedLine Citation:
PMID:  12629267     Owner:  NLM     Status:  MEDLINE    
CONTEXT: Pancreatic neoplasms are an uncommon aetiology of acute pancreatitis. Pancreatic neuroendocrine tumours are a rare subgroup of pancreatic neoplasms. CASE REPORT: We report on three patients having acute pancreatitis secondary to pancreatic neuroendocrine tumours, one of them with severe pancreatitis, and review the published cases up to now. Only 22 patients with acute pancreatitis secondary to pancreatic neuroendocrine tumours have been reported (including the present cases). Most of these cases were of non-functioning neoplasms and the course of the pancreatitis tended to be mild. In the most recent reports and in the present cases, the initial diagnostic method was CT scan. Less than half had metastases when the tumour was diagnosed and mortality from these neoplasms reached approximately 50%. CONCLUSIONS: Pancreatic neuroendocrine tumours can cause acute pancreatitis even in patients under 50 years of age. On many occasions, the tumours are non-functioning; therefore, acute pancreatitis may be the first clinical symptom. Consequently, faced with acute pancreatitis of unknown origin, a non-functioning neuroendocrine tumour should be ruled out.
Pilar Griñó; Juan Martínez; Emilio Griñó; Fernando Carnicer; Sergio Alonso; Helena Pérez-Berenguer; Miguel Pérez-Mateo
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  JOP : Journal of the pancreas     Volume:  4     ISSN:  1590-8577     ISO Abbreviation:  JOP     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-03-11     Completed Date:  2003-03-17     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  101091810     Medline TA:  JOP     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  104-10     Citation Subset:  IM    
Department of Gastroenterology, Hospital General Universitario de Alicante, Alicante, Spain.
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MeSH Terms
Acute Disease
Fatal Outcome
Multiple Organ Failure / etiology,  pathology
Neuroendocrine Tumors / complications*,  pathology
Pancreatic Neoplasms / complications*,  pathology
Pancreatitis / etiology*,  pathology

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