Document Detail


Acute pancreatitis: radiologic scores in predicting severity and outcome.
MedLine Citation:
PMID:  19437067     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute pancreatitis (AP) is a common inflammatory disease which can be mild and self-limiting without complications or severe with prolonged hospitalization, high morbidity, and high mortality. Different radiological scoring systems to predict severity and outcome in AP have been developed since the early 1990s. In the meantime, new insights in the pathophysiology of AP and consequently, therapeutic management of these patients have been introduced. The purpose of this review is therefore (1) to describe the current terminology and new concepts in the pathophysiology, (2) to outline the long existing and newly developed radiological scoring systems in prediction of severity and outcome with their respective advantages and limitations, and (3) to define the role of radiological prognostic scoring systems in the new environment of perception of the last decade. Risk stratification in AP requires scoring systems that can be calculated early in the course of disease which allows time for intervention. For that reason, scoring systems based on necrosis are not useful in severity prediction. The recent developed radiological scoring systems based on signs of systemic inflammatory response syndrome and organ dysfunction are promising in prediction of severity early after onset of AP.
Authors:
Louke J Delrue; Jan J De Waele; Philippe O Duyck
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Publication Detail:
Type:  Case Reports; Journal Article; Review     Date:  2009-05-13
Journal Detail:
Title:  Abdominal imaging     Volume:  35     ISSN:  1432-0509     ISO Abbreviation:  Abdom Imaging     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-06-16     Completed Date:  2010-09-23     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9303672     Medline TA:  Abdom Imaging     Country:  United States    
Other Details:
Languages:  eng     Pagination:  349-61     Citation Subset:  IM    
Affiliation:
Department of Radiology, Ghent University Hospital, Belgium. louke.delrue@uzgent.be
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MeSH Terms
Descriptor/Qualifier:
APACHE
Abscess / radiography
Acute Disease
Humans
Necrosis
Pancreatic Diseases / radiography
Pancreatic Pseudocyst / radiography
Pancreatitis / etiology,  radiography*
Prognosis
Risk Assessment
Severity of Illness Index
Tomography, X-Ray Computed
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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