| Acute pancreatitis - ischaemia or hyperaemia? | |
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MedLine Citation:
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PMID: 7432249 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There is no accepted specific treatment for acute pancreatitis in man in spite of extensive investigations. Evidence is presented based on histology, vascular and blood flow studies to support the hypothesis that acute pancreatitis is unlike most inflammatory conditions since a rapid and severe ischaemia develops in the pancreas. In dogs for example there is an instant and maintained reduction in pancreatic blood flow reducing by 72% at 3 hours. Various treatments have been advocated in acute pancreatitis. Based upon the effect of dextran 40 in improving pancreatic blood flow and percentage cardiac output, it would appear to be a treatment of choice in acute pancreatitis. |
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Authors:
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L A Donaldson; S N Joffe; W G Schenk |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Medical hypotheses Volume: 6 ISSN: 0306-9877 ISO Abbreviation: Med. Hypotheses Publication Date: 1980 Mar |
Date Detail:
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Created Date: 1981-01-29 Completed Date: 1981-01-29 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7505668 Medline TA: Med Hypotheses Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 329-36 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Cardiac Output Humans Ischemia / complications* Models, Biological Pancreas / blood supply*, physiopathology Pancreatitis / etiology* Regional Blood Flow |
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