Document Detail


Acute-onset chronic inflammatory demyelinating polyneuropathy with focal segmental glomerulosclerosis.
MedLine Citation:
PMID:  24726719     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Inflammatory neuropathies have been reported to occur in association with nephrotic syndrome. Their underlying immuno-pathogenic mechanisms remain unknown. A 50-year-old woman concurrently presented with acute-onset chronic inflammatory demyelinating polyneuropathy and nephrotic syndrome secondary to focal segmental glomerulosclerosis. Both neuropathy and proteinuria improved after plasma exchange and steroids. Literature review of cases of concurrent inflammatory neuropathies and nephrotic syndrome revealed similar neuro-renal presentations. This neuro-renal condition may be mediated by autoantibodies targeting myelin and podocytes.
Authors:
Amy May Lin Quek; Derek Soon; Yee Cheun Chan; Thomas Paulraj Thamboo; Nobuhiro Yuki
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-3-29
Journal Detail:
Title:  Journal of the neurological sciences     Volume:  -     ISSN:  1878-5883     ISO Abbreviation:  J. Neurol. Sci.     Publication Date:  2014 Mar 
Date Detail:
Created Date:  2014-4-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375403     Medline TA:  J Neurol Sci     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier B.V. All rights reserved.
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