Document Detail

Acute obstructive uric acid nephropathy after treatment of neoplastic adenopathy.
MedLine Citation:
PMID:  7221659     Owner:  NLM     Status:  MEDLINE    
Patients with lymphoma and leukemia are at increased risk of therapy-related sudden increase in the serum uric acid level, with resultant precipitation and obstruction in the more acidic and concentrated distal nephron. Appropriate pretreatment measures can prevent intrarenal crystal formation. The acute obstruction responds well to treatment, and aggressive measures are indicated.
R H Fitzgerald; K M Wallace; A S Baker
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  74     ISSN:  0038-4348     ISO Abbreviation:  South. Med. J.     Publication Date:  1981 Apr 
Date Detail:
Created Date:  1981-06-23     Completed Date:  1981-06-23     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  424-6     Citation Subset:  AIM; IM    
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MeSH Terms
Acute Disease
Chlorambucil / therapeutic use
Constriction, Pathologic
Kidney Diseases / etiology*
Leukemia, Lymphoid / complications*,  drug therapy,  radiotherapy
Middle Aged
Prednisone / therapeutic use
Uric Acid / blood*
Reg. No./Substance:
305-03-3/Chlorambucil; 53-03-2/Prednisone; 69-93-2/Uric Acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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