| Acute necrotizing lepromatous lymphadenitis: an erythema-nodosum-leprosum-like reaction in lymph nodes. | |
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MedLine Citation:
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PMID: 4300767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Histological examination of lymph-node biopsy specimens in 12 patients with erythema nodosum leprosum showed almost complete replacement of the node by lepromatous granuloma, together with considerable polymorph infiltration. Ziehl-Neelsen staining demonstrated numerous Mycobacterium leprae present in the nodes. The majority of these patients were very ill, and responded to prednisolone or corticotrophin.It is suggested that the histological appearances may represent an intensive inflammatory response in the lymph nodes followed by avascular aseptic necrosis. |
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Authors:
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A B Karat; S Karat; C K Job; D Sudarsanam |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: British medical journal Volume: 4 ISSN: 0007-1447 ISO Abbreviation: Br Med J Publication Date: 1968 Oct |
Date Detail:
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Created Date: 1968-12-02 Completed Date: 1968-12-02 Revised Date: 2010-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0372673 Medline TA: Br Med J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 223-4 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenocorticotropic Hormone
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therapeutic use Erythema Nodosum / drug therapy, etiology, pathology* Histological Techniques Humans Leprosy / complications, pathology* Lymph Nodes / microbiology, pathology* Lymphadenitis / physiopathology* Mycobacterium leprae / isolation & purification Necrosis / complications Prednisolone / therapeutic use |
| Chemical | |
Reg. No./Substance:
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50-24-8/Prednisolone; 9002-60-2/Adrenocorticotropic Hormone |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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