Document Detail

Acute myopia induced by topiramate: report of a case and review of the literature.
MedLine Citation:
PMID:  15805668     Owner:  NLM     Status:  MEDLINE    
Topiramate, a new anticonvulsant, is also used for the prophylaxis of migraine and cluster headache. A serious but not often discussed side effect of the drug is the development of acute myopia and acute angle-closure glaucoma in the early stage of therapy that subsides rapidly with prompt discontinuation. One such case is reported here and the relevant literature in this regard is also reviewed.
Kalyan B Bhattacharyya; S Basu
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Neurology India     Volume:  53     ISSN:  0028-3886     ISO Abbreviation:  Neurol India     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-04-04     Completed Date:  2005-05-18     Revised Date:  2013-08-21    
Medline Journal Info:
Nlm Unique ID:  0042005     Medline TA:  Neurol India     Country:  India    
Other Details:
Languages:  eng     Pagination:  108-9     Citation Subset:  IM    
Department of Neurology, Calcutta National Medical College and Hospital, Kolkata 700-042, West Bengal, India.
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MeSH Terms
Acute Disease
Anticonvulsants / adverse effects*
Fructose / adverse effects*,  analogs & derivatives*
Headache / drug therapy*
Myopia / chemically induced*
Reg. No./Substance:
0/Anticonvulsants; 0H73WJJ391/topiramate; 30237-26-4/Fructose
Comment In:
Neurol India. 2005 Jun;53(2):243; author reply 243   [PMID:  16010078 ]

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