Document Detail

Acute myocardial injury following penicillin-associated anaphylactic reaction in a patient with normal coronary arteries.
MedLine Citation:
PMID:  18030189     Owner:  NLM     Status:  MEDLINE    
Cardiac involvement is uncommon and important clinical finding during an anaphylactic reaction, and it occurs primarily in subjects with underlying ischemic heart disease. The main mechanism proposed is the vasospasm of coronary arteries. We report a rare case of acute ST-elevation myocardial injury after penicillin-induced anaphylaxis in a patient with normal coronary arteries. Physicians should be alert for such a serious complication in order to diagnose it early and treat properly. We suggest that cardiac monitoring and appropriate therapy should be available for patients with severe allergic reactions especially during parenteral administration of epinephrine.
Zachary Z Brener; Igor Zhuravenko; Michael Bergman
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of the medical sciences     Volume:  334     ISSN:  0002-9629     ISO Abbreviation:  Am. J. Med. Sci.     Publication Date:  2007 Oct 
Date Detail:
Created Date:  2007-11-21     Completed Date:  2007-12-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370506     Medline TA:  Am J Med Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  305-7     Citation Subset:  AIM; IM    
Department of Medicine, Beth Israel Medical Center, 350 E. 17th Street, New York, NY 10003, USA.
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MeSH Terms
Acute Disease
Anaphylaxis / chemically induced*,  complications*
Cardiomyopathies / diagnosis,  etiology*,  physiopathology
Coronary Vasospasm / complications,  physiopathology
Coronary Vessels / physiology*
Middle Aged
Penicillins / adverse effects*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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