Document Detail

Acute myocardial infarction probably caused by paradoxical embolus in a pregnant woman.
MedLine Citation:
PMID:  14966073     Owner:  NLM     Status:  MEDLINE    
A 19 year old pregnant woman presented to the coronary care unit with an acute anterior myocardial infarction. She was treated with primary percutaneous transluminal coronary angioplasty of the proximal left anterior descending coronary artery. Ultrasound examination showed patent foramen ovale (PFO) and atrial septal aneurysm. The patient was a heterozygote carrier of factor V Leiden. Despite the lack of a clear clue, it was considered that the pathophysiological cause of this infarction was a paradoxical embolus in the left coronary artery. Pregnancy and factor V Leiden carriership are associated with increased risk of venous thromboembolism and the association between PFO and atrial septal aneurysm is a strong risk factor for systemic embolisation.
P Agostoni; G Gasparini; G Destro
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Heart (British Cardiac Society)     Volume:  90     ISSN:  1468-201X     ISO Abbreviation:  Heart     Publication Date:  2004 Mar 
Date Detail:
Created Date:  2004-02-17     Completed Date:  2004-03-16     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  9602087     Medline TA:  Heart     Country:  England    
Other Details:
Languages:  eng     Pagination:  e12     Citation Subset:  AIM; IM    
Institute of Cardiology, Ospedale Civile Maggiore, University of Verona, Verona, Italy.
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MeSH Terms
Angioplasty, Balloon, Coronary
Coronary Stenosis / etiology,  radiography
Embolism, Paradoxical / complications*
Factor V / genetics
Heart Aneurysm / ultrasonography
Heart Septal Defects, Atrial / ultrasonography
Mutation / genetics
Myocardial Infarction / etiology*,  therapy
Pregnancy Complications, Cardiovascular / etiology*
Reg. No./Substance:
0/factor V Leiden; 9001-24-5/Factor V

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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