| Acute myocardial infarction in pregnancy and the puerperium: a population-based study. | |
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MedLine Citation:
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PMID: 15738011 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To estimate the population-based incidence and pregnancy outcomes of acute myocardial infarction (MI) in pregnancy. METHODS: Maternal and newborn hospital discharge records were linked to birth/death certificates for the 10-year period January 1, 1991, to December 30, 2000, for the majority (98%) of deliveries in California. This database was searched for the diagnosis of acute MI, demographic characteristics, and pregnancy outcomes. Patients were divided into 4 groups: antenatal diagnosis, intrapartum diagnosis, up to 6-week postpartum diagnosis, and those without the diagnosis of acute MI. All groups were compared by Student t test or chi(2) or both, where appropriate. RESULTS: A total of 151 women had an acute MI during the antepartum (38%), intrapartum (21%), or 6-week postpartum (41%) period, giving an incidence rate of 1 in 35,700 deliveries. The incidence rate increased over the study period. The maternal mortality rate was 7.3%, and maternal death only occurred in women with an acute MI before or at delivery (P < .01). Compared with women who did not have an acute MI, those with one were more likely to be older (30% were older than 35 years compared with 10%), multiparous (78% compared with 61%), non-Hispanic white (40% compared with 35%) or African Americans (15% compared with 7%). All measures of maternal and neonatal morbidity were increased in the acute MI group compared with those without an acute MI. Multivariate analysis identified chronic hypertension, diabetes, advancing maternal age, eclampsia, and severe preeclampsia as independent risk factors for acute MI. CONCLUSION: Acute MI during pregnancy remains a rare event, with significant maternal, fetal, and neonatal morbidity and mortality and maternal mortality limited to the antepartum and intrapartum period. |
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Authors:
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Heidi E Ladner; Beate Danielsen; William M Gilbert |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 105 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2005 Mar |
Date Detail:
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Created Date: 2005-03-01 Completed Date: 2005-04-07 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 480-4 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, University of California, Davis, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult California / epidemiology Female Fetal Death Humans Incidence Infant Mortality Infant, Low Birth Weight Infant, Newborn Myocardial Infarction / diagnosis, epidemiology*, mortality Obstetric Labor Complications / diagnosis, epidemiology, mortality Obstetric Labor, Premature / etiology Pregnancy Pregnancy Complications, Cardiovascular / diagnosis, epidemiology*, mortality Puerperal Disorders / diagnosis, epidemiology*, mortality Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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