Document Detail

Acute myocardial infarction after bone marrow transplantation: an unsuspected late complication.
MedLine Citation:
PMID:  12601497     Owner:  NLM     Status:  MEDLINE    
Acute myocardial infarction is a common disease rarely seen as a complication of bone marrow transplantation in young patients. We report on a 25-year-old patient 3.5 years after bone marrow transplantation who suffered an acute anterior wall myocardial infarction complicated by cardiogenic shock. The patient was treated with thrombolysis and emergent coronary angioplasty but died a few hours following admission. We suggest that the combination of low-dose chest irradiation and prolonged immunosuppression with graft-versus-host disease contributed to the development of the coronary artery disease in this patient. Though rarely encountered, physicians caring for young patients after bone marrow transplantation should be aware of potential ischemic complications.
M E Gatt; D Liebster; D Leibowitz; Y Matzner
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2003-02-04
Journal Detail:
Title:  Annals of hematology     Volume:  82     ISSN:  0939-5555     ISO Abbreviation:  Ann. Hematol.     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-02-25     Completed Date:  2003-05-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9107334     Medline TA:  Ann Hematol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  136-8     Citation Subset:  IM    
Department of Internal Medicine, Hadassah University Hospital Mount Scopus, Hadassah-Hebrew University Medical School, Jerusalem, Israel.
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MeSH Terms
Bone Marrow Transplantation / adverse effects*
Fatal Outcome
Graft vs Host Disease / complications,  drug therapy
Immunosuppression / adverse effects
Myelodysplastic Syndromes / complications,  therapy
Myocardial Infarction / etiology*
Time Factors
Whole-Body Irradiation / adverse effects

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