| Acute myelopathy selectively involving lumbar anterior horns following intranasal insufflation of ecstasy and heroin. | |
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MedLine Citation:
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PMID: 21686691 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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We report a patient who developed acute myelopathy after intranasal insufflation of amphetamines and heroin. The functional prognosis was very poor; after 4 months, she remained paraplegic. MRI imaging showed selective T2 hyperintensity and intense enhancement confined to the spinal anterior horns and lumbar nerve roots and plexus. This unique MRI pattern, together with neurophysiological data, suggests that the pathological process at the first primary affected spinal anterior horns (SAH), conditioning motoneuron cell death, and then nerve roots and lumbar plexus as a consequence of wallerian degeneration. |
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Authors:
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Nilo Riva; Nilo Riva; Paolo Morana; Federica Cerri; Simonetta Gerevini; Stefano Amadio; Fabio Formaglio; Giancarlo Comi; Mauro Comola; Ubaldo Del Carro |
Publication Detail:
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Type: Journal Article Date: 2009-01-23 |
Journal Detail:
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Title: BMJ case reports Volume: 2009 ISSN: 1757-790X ISO Abbreviation: BMJ Case Rep Publication Date: 2009 |
Date Detail:
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Created Date: 2011-06-20 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101526291 Medline TA: BMJ Case Rep Country: England |
Other Details:
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Languages: eng Pagination: - Citation Subset: - |
Affiliation:
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San Raffaele Scientific Institute, Department of Neuroradiology, Via Olgettina 60, Milan, 20132, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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