| Acute myeloid leukemia diagnosis in the 21st century. | |
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MedLine Citation:
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PMID: 20923295 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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CONTEXT: Rapid advances in understanding the molecular biology of acute myeloid leukemia are transforming the approach to diagnosis, prognostication, and treatment of these cases. OBJECTIVE: To briefly review the current state of AML classification with a particular emphasis on the role of molecular studies and their impact on the management of acute myeloid leukemia and other malignancies. DATA SOURCES: Current literature and experience of the authors. CONCLUSIONS: While morphology, immunophenotyping, cytogenetics, and clinical history continue to play an important role, an increasing number of molecular tests are now required to properly classify these cases. |
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Authors:
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Bryan L Betz; Jay L Hess |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Archives of pathology & laboratory medicine Volume: 134 ISSN: 1543-2165 ISO Abbreviation: Arch. Pathol. Lab. Med. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7607091 Medline TA: Arch Pathol Lab Med Country: United States |
Other Details:
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Languages: eng Pagination: 1427-33 Citation Subset: AIM; IM |
Affiliation:
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Molecular Diagnostics Laboratory, University of Michigan Health System, Ann Arbor, MI 48105-3450, USA. bbetz@med.umich.edu |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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