| Acute myelogenous leukemia mimicking a hemolysis, elevated liver enzymes, and low platelets syndrome during pregnancy: case report and review of the literature. | |
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MedLine Citation:
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PMID: 17094046 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Acute leukemia is a rare malignancy of pregnancy. When it develops, there are many complications to consider and management becomes exceedingly difficult. We report a case of acute myelogenous leukemia presenting as preeclampsia and fetal demise at 36 weeks of gestation. A 30-year-old multigravida presented with intrauterine fetal demise at 36 weeks' gestation, hypertension, and thrombocytopenia. The patient received platelet and packed red blood cell transfusion, with concurrent prophylactic magnesium sulfate and dexamethasone treatment. Following labor induction, the patient delivered a nonviable female fetus and suffered a stroke postpartum. Peripheral smear and flow cytometry revealed the patient had acute myeloid leukemia with prominent monocytic differentiation. The patient expired on postpartum day six. Acute leukemia during the pregnancy is associated with an unfavorable outcome. |
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Authors:
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Ramzi Aboujaoude; Jesus Alvarez; Manuel Alvarez; Abdullah Al Khan |
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Publication Detail:
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Type: Case Reports; Journal Article; Review Date: 2006-11-08 |
Journal Detail:
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Title: American journal of perinatology Volume: 24 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2007-01-18 Completed Date: 2007-03-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 1-4 Citation Subset: IM |
Affiliation:
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New Jersey Medical School, University of Medicine and Dentistry, Newark, New Jersey, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Diagnosis, Differential Fatal Outcome Female Fetal Death Hemolysis Humans Leukemia, Monocytic, Acute / blood, complications, diagnosis*, pathology Liver / enzymology Platelet Transfusion Pregnancy Pregnancy Complications, Neoplastic / blood, diagnosis*, pathology Pregnancy Trimester, Third Prenatal Diagnosis* Thrombocytopenia / blood, etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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