Document Detail


Acute multifocal skin necrosis: synergism between invasive streptococcal infection and cocaine-induced tissue ischaemia?
MedLine Citation:
PMID:  8800309     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 30-year-old pregnant woman with full thickness skin necrosis following parenteral abuse of cocaine and heroine is described. Three lesions occurred simultaneously on the trunk and right knee subsequent to an abscess on the left thigh from which S. pyogenes group A and S. aureus were isolated. Histology revealed necrotic subcutaneous tissue with obliterated vessels and a mixed inflammatory infiltrate. The sequence of events suggests a synergism between the effects of bacterial proteases and cocaine-induced impairment of soft tissue perfusion. In the present case, this synergism may have been further enhanced by decreased cocaine tolerance during pregnancy.
Authors:
P H Hoeger; G Haupt; E Hoelzle
Related Documents :
8206019 - Human adverse reproductive outcomes and electromagnetic field exposures: review of epid...
17484709 - A review of policies on alcohol use during pregnancy in australia and other english-spe...
15327589 - First-trimester exposure to amoxycillin/clavulanic acid: a prospective, controlled study.
7488569 - Does prenatal exposure to influenza in mice induce pyramidal cell disarray in the dorsa...
17300889 - Effect of infrasound on cochlear damage from exposure to a 4 khz octave band of noise.
7898419 - Update: trends in fetal alcohol syndrome--united states, 1979-1993.
8377969 - Differential diagnosis of the nonvisualized fetal urinary bladder by transvaginal sonog...
10380299 - Screening efficacy of the subcutaneous tissue width/femur length ratio for fetal macros...
7753939 - Analytic work concerning motherhood.
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta dermato-venereologica     Volume:  76     ISSN:  0001-5555     ISO Abbreviation:  Acta Derm. Venereol.     Publication Date:  1996 May 
Date Detail:
Created Date:  1997-04-08     Completed Date:  1997-04-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370310     Medline TA:  Acta Derm Venereol     Country:  NORWAY    
Other Details:
Languages:  eng     Pagination:  239-41     Citation Subset:  IM    
Affiliation:
Department of Dermatology, University of Hamburg, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Cocaine*
Female
Heroin Dependence / complications
Humans
Necrosis
Pregnancy
Pregnancy Complications*
Pregnancy Complications, Infectious / pathology
Skin / pathology*
Skin Diseases, Bacterial / complications,  pathology*
Streptococcal Infections / complications,  pathology*
Substance Abuse, Intravenous / complications*
Chemical
Reg. No./Substance:
50-36-2/Cocaine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Treatment of ischaemic digital ulcers and prevention of gangrene with intravenous iloprost in system...
Next Document:  Brain oedema in patients with intracranial meningioma. Correlation between clinical, radiological, a...