| Acute metabolic alkalosis in cystic fibrosis: prospective study and review of the literature. | |
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MedLine Citation:
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PMID: 9058367 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Between January 1993 and April 1994, 5 patients with cystic fibrosis, aged 4-9 months, were admitted to the Department of Pediatrics, University of Berne, Switzerland, with acute, severe metabolic alkalosis (sodium < 133 mmol/l, plasma potassium < 3.5, chloride < 85, bicarbonate > 35.0 mmol/l, blood pH > 7.43). 87 cases of acute metabolic alkalosis complicating cystic fibrosis reported in the literature between 1951 and 1995 were also reviewed. Our cases and those described in the literature demonstrate that acute metabolic alkalosis occurs in patients aged 2 years or less. Anorexia, vomiting, respiratory exacerbation, fever, and body weight loss often precede metabolic alkalosis. Furthermore, metabolic alkalosis is a common initial presentation of cystic fibrosis, suggesting that this diagnosis should be considered in the context of unexplained metabolic alkalosis. |
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Authors:
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S Mauri; G Pedroli; A Rüdeberg; R Laux-End; R Monotti; M G Bianchetti |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Mineral and electrolyte metabolism Volume: 23 ISSN: 0378-0392 ISO Abbreviation: Miner Electrolyte Metab Publication Date: 1997 |
Date Detail:
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Created Date: 1997-05-09 Completed Date: 1997-05-09 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7802196 Medline TA: Miner Electrolyte Metab Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 33-7 Citation Subset: IM |
Affiliation:
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Department of Pediatrics, University of Berne, Switzerland. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adolescent Adult Alkalosis / etiology* Child Child, Preschool Chlorides / metabolism Cystic Fibrosis / complications* Female Humans Infant Male Prospective Studies |
| Chemical | |
Reg. No./Substance:
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0/Chlorides |
| Comments/Corrections | |
Comment In:
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Miner Electrolyte Metab. 1999 May-Jun;25(3):210
[PMID:
10436408
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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