Document Detail

Acute massive pulmonary hemorrhage after craniotomy in a patient with systemic lupus erythematosus.
MedLine Citation:
PMID:  15692631     Owner:  NLM     Status:  MEDLINE    
Acute massive pulmonary hemorrhage (AMPH) is a rare life-threatening complication of systemic lupus erythematosus (SLE). We report a lupus nephritis patient with active disease, in whom AMPH developed after craniotomy for brain injury. Computed tomography scan of the brain revealed a subdural hemorrhage and intracranial hemorrhage with a midline shift, indicating increased intracranial pressure (IICP). Neurogenic pulmonary edema (NPE) was suspected 5 days after operation due to dyspnea and chest radiograph findings of bilateral infiltrations. Seven days after the craniotomy, she had bloody sputum, a sudden drop in blood hemoglobin level (from 12.3 g/dL to 8.8 g/dL), and diffuse alveolar infiltrates in both lung fields. All of these features were characteristic manifestations of AMPH. Complete blood count disclosed mild thrombocytopenia (88,000/mm3). We believe that in an SLE patient, IICP or NPE might be risk factors in the development of AMPH.
Shu-Jen Chang; Yu-Shu Yen; An-Ping Huo; Shinn-Shing Lee; De-Feng Huang
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi     Volume:  38     ISSN:  1684-1182     ISO Abbreviation:  J Microbiol Immunol Infect     Publication Date:  2005 Feb 
Date Detail:
Created Date:  2005-02-04     Completed Date:  2005-03-31     Revised Date:  2007-06-21    
Medline Journal Info:
Nlm Unique ID:  100956211     Medline TA:  J Microbiol Immunol Infect     Country:  China (Republic: 1949- )    
Other Details:
Languages:  eng     Pagination:  69-72     Citation Subset:  IM    
Section of Allergy, Immunology, and Rheumatology, Department of Medicine, Cheng Hsin Rehabilitation Medical Center, Taipei, Taiwan.
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MeSH Terms
Craniotomy / adverse effects*
Hemorrhage / etiology*
Intracranial Pressure
Lung Diseases / etiology*
Lupus Erythematosus, Systemic / complications*
Middle Aged
Pulmonary Edema / complications

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