Document Detail


Acute magnesium toxicity in an obstetric patient undergoing general anaesthesia for caesarean delivery.
MedLine Citation:
PMID:  20219345     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Magnesium is commonly used in the prevention of eclampsia. Reports of acute toxicity are rare and we are not aware of detailed management algorithms. We present a case of acute magnesium toxicity presenting as ventilatory impairment and failure to rouse adequately from general anaesthesia. The patient was managed with controlled ventilation, further sedation, intravenous calcium gluconate, forced diuresis and dextrose-insulin infusion. We present a guideline for the management of life-threatening magnesium toxicity and discuss measures that may prevent future similar occurrences.
Authors:
N J McDonnell; N A Muchatuta; M J Paech
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2010-03-09
Journal Detail:
Title:  International journal of obstetric anesthesia     Volume:  19     ISSN:  1532-3374     ISO Abbreviation:  Int J Obstet Anesth     Publication Date:  2010 Apr 
Date Detail:
Created Date:  2010-03-29     Completed Date:  2010-12-27     Revised Date:  2011-01-28    
Medline Journal Info:
Nlm Unique ID:  9200430     Medline TA:  Int J Obstet Anesth     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  226-31     Citation Subset:  IM    
Copyright Information:
Crown Copyright 2009. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Department of Anaesthesia and Pain Medicine, King Edward Memorial Hospital for Women, Perth, Western Australia, Australia. nolan.mcdonnell@health.wa.gov.au
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Algorithms
Anesthesia, General / methods*
Anesthesia, Obstetrical / methods*
Cesarean Section
Female
Humans
Magnesium Sulfate / administration & dosage,  poisoning*
Medication Errors*
Pre-Eclampsia / drug therapy*
Pregnancy
Respiratory Insufficiency / chemically induced*,  therapy
Treatment Outcome
Chemical
Reg. No./Substance:
7487-88-9/Magnesium Sulfate
Comments/Corrections
Comment In:
Int J Obstet Anesth. 2011 Jan;20(1):92-3   [PMID:  21134738 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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