Document Detail


[Acute lung injury and acute respiratory distress syndrome: a genomic perspective].
MedLine Citation:
PMID:  21429625     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Genomics have allowed important advances in the knowledge of the etiology and pathogenesis of complex disease entities such as acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Genomic medicine aims to personalize and optimize diagnosis, prognosis and treatment by determining the influence of genetic polymorphisms in specific diseases. The scientific community must cope with the important challenge of securing rapid transfer of knowledge to clinical practice, in order to prevent patients from becoming exposed to unnecessary risks. In the present article we describe the main concepts of genomic medicine pertaining to ALI/ARDS, and its currently recognized clinical applications.
Authors:
P Cardinal-Fernández; N Nin; J A Lorente
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Publication Detail:
Type:  English Abstract; Journal Article; Review     Date:  2011-03-22
Journal Detail:
Title:  Medicina intensiva / Sociedad Española de Medicina Intensiva y Unidades Coronarias     Volume:  35     ISSN:  1578-6749     ISO Abbreviation:  Med Intensiva     Publication Date:    2011 Aug-Sep
Date Detail:
Created Date:  2011-07-15     Completed Date:  2011-12-19     Revised Date:  2012-01-18    
Medline Journal Info:
Nlm Unique ID:  9207689     Medline TA:  Med Intensiva     Country:  Spain    
Other Details:
Languages:  spa     Pagination:  361-72     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier España, S.L. y SEMICYUC. All rights reserved.
Affiliation:
Unidad de Cuidados Intensivos, CASMU-IAMPP-Hospital Central de las Fuerzas Armadas, Montevideo, Uruguay. pablocardinal@hotmail.com
Vernacular Title:
Lesión pulmonar aguda y síndrome de distrés respiratorio agudo: una perspectiva genómica.
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MeSH Terms
Descriptor/Qualifier:
Acute Lung Injury / genetics*
Genomics*
Humans
Polymorphism, Genetic
Respiratory Distress Syndrome, Adult / genetics*

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