Document Detail

Acute and longer-term effects of risperidone in a case of first-episode catatonic schizophrenia.
MedLine Citation:
PMID:  10958259     Owner:  NLM     Status:  MEDLINE    
This case report documents the response of a young, first-episode, neuroleptic naive male with severe catatonic schizophrenia to the novel antipsychotic, risperidone. Initial assessments included the Positive and Negative Syndrome Scales, Global Assessment of Function and the Extrapyramidal Symptom Rating Scale. These were repeated at discharge from hospital and during a 3.5 year outpatient follow-up. Neuroimaging (computed tomography, magnetic resonance imaging and single photon emission tomography) along with electroencephalogram and laboratory examinations were completed. Response to risperidone was prompt, dramatic and sustained over the follow-up period. Possible neurochemical brain mechanisms resulting in catatonia and the role of serotonin/dopamine antagonists such as risperidone are discussed. No other literature on the effect of risperidone in the treatment of severe catatonic schizophrenia in a first-episode patient has been reported.
L C Kopala; C Caudle
Related Documents :
22362829 - Clinical use of skype: a review of the evidence base.
10958259 - Acute and longer-term effects of risperidone in a case of first-episode catatonic schiz...
24228129 - Florid diffuse peritoneal deciduosis mimicking carcinomatosis in a primigravida patient...
23667379 - Extrapelvic uterus-like masses presenting as colonic submucosal tumor: a case study and...
22505959 - Hepatoblastoma in adult: review of the literature.
22618209 - Anatomy and histology of apical support: a literature review concerning cardinal and ut...
8183519 - Late onset endophthalmitis associated with filtering blebs.
22487279 - Orbital involvement in pott's puffy tumor: a systematic review of published cases.
22263209 - Luxatio erecta: case series with review of diagnostic and management principles.
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of psychopharmacology (Oxford, England)     Volume:  12     ISSN:  0269-8811     ISO Abbreviation:  J. Psychopharmacol. (Oxford)     Publication Date:  1998  
Date Detail:
Created Date:  2000-09-15     Completed Date:  2000-09-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8907828     Medline TA:  J Psychopharmacol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  314-7     Citation Subset:  IM    
Department of Psychiatry, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Antipsychotic Agents / therapeutic use*
Movement Disorders / complications,  drug therapy
Psychiatric Status Rating Scales
Risperidone / therapeutic use*
Schizophrenia, Catatonic / complications,  drug therapy*,  psychology
Reg. No./Substance:
0/Antipsychotic Agents; 106266-06-2/Risperidone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The SSRI discontinuation syndrome.
Next Document:  A prospective naturalistic study of 326 panic-agoraphobic patients treated with antidepressants.