Document Detail


Acute and long-term hemodynamic effects of sesame oil consumption in hypertensive men.
MedLine Citation:
PMID:  22947362     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
J Clin Hypertens (Greenwich). 2012; 14:630-636. © 2012 Wiley Periodicals, Inc. The possible effects of sesame oil on hemodynamics are unknown. The aim of the study was to investigate the acute and long-term effects of sesame oil on hemodynamic responses in hypertensive men. The authors enrolled 30 hypertensive men in a two-phase study. In the first phase, patients consumed 35 g of either sesame oil or control oil. Central and peripheral blood pressure, pulse wave velocity, augmentation index (AI), C-reactive protein, tumor necrosis factor α, malonydealdehyde, and total antioxidant capacity (TAC) were assessed at fast and 2 hours postprandially. In the second phase, patients consumed 35 g of either sesame oil or control oil daily for 2 months. The above-mentioned parameters were assessed before and following 15, 30, and 60 days of oil consumption. Sesame oil decreased central and peripheral diastolic pressures 1 hour postprandially (P=.006). Fifteen days of sesame oil intake decreased peripheral systolic blood pressure (P=.016) and heart rate-corrected AI75 (P=.017) and increased TAC (P=.007). This is the first study to demonstrate a favorable acute and long-term effect of sesame oil on hemodynamics in hypertensive men. Further research is warranted to establish the potential protective role of sesame oil.
Authors:
Kalliopi Karatzi; Kimon Stamatelopoulos; Marita Lykka; Pigi Mantzouratou; Sofia Skalidi; Efstathios Manios; George Georgiopoulos; Nikolaos Zakopoulos; Christos Papamichael; Labros S Sidossis
Publication Detail:
Type:  Journal Article     Date:  2012-05-24
Journal Detail:
Title:  Journal of clinical hypertension (Greenwich, Conn.)     Volume:  14     ISSN:  1751-7176     ISO Abbreviation:  J Clin Hypertens (Greenwich)     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-05     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100888554     Medline TA:  J Clin Hypertens (Greenwich)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  630-6     Citation Subset:  IM    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Affiliation:
From the Department of Nutrition and Dietetics, Harokopio University, Athens, Greece;the Vascular Laboratory, Department of Clinical Therapeutics, Alexandra University Hospital, Athens, Greece;the Department of Internal Medicine-Geriatrics, Sealy Center on Aging, Institute for Translational Sciences and Shriners Hospital for Children, University of Texas Medical Branch at Galveston, Galveston, TX.
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