| Acute liver injury associated with the use of herbal preparations containing glucosamine: three case studies. | |
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MedLine Citation:
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PMID: 21887162 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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The use of complementary and alternative medicines is becoming increasingly popular in Western society. As a result the number of reported adverse reactions is increasing. Glucosamine is a herbal remedy commonly used to ease joint pain in osteoarthritis, and only two previous reports of hepatotoxicity have been published in the scientific literature. The present report describes three patients who developed acute liver injury following exposure to glucosamine; one patient made a complete recovery on cessation of ingestion, the second developed chronic hepatitis and the third died following progression to fulminant hepatic failure. A diagnosis of glucosamine-induced hepatotoxicity was made based on the temporal relationship between onset of liver injury and glucosamine ingestion, exclusion of all other potential aetiologies and, in the two surviving cases, improvement in condition on withdrawal of the supplement. |
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Authors:
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Aileen Smith; John Dillon |
Publication Detail:
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Type: Journal Article Date: 2009-09-02 |
Journal Detail:
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Title: BMJ case reports Volume: 2009 ISSN: 1757-790X ISO Abbreviation: BMJ Case Rep Publication Date: 2009 |
Date Detail:
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Created Date: 2011-09-02 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101526291 Medline TA: BMJ Case Rep Country: England |
Other Details:
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Languages: eng Pagination: - Citation Subset: - |
Affiliation:
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Ninewells Hospital and Medical School, Gastroenterology, Wards 5/6, Ninewells Hospital, Dundee, DD1 9SY, UK. |
Export Citation:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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