| Acute liver failure at 26 weeks' gestation in a patient with sickle cell disease. | |
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MedLine Citation:
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PMID: 19790148 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Orthotopic liver transplantation (OLT) for acute liver failure (ALF) during pregnancy is an uncommon occurrence with variable outcomes. In pregnancy-related liver failure, prompt diagnosis and immediate delivery are essential for a reversal of the underlying process and for maternal and fetal survival. In rare cases, the reason for ALF during pregnancy is either unknown or irreversible, and thus OLT may be necessary. This case demonstrates the development of cryptogenic ALF during the 26th week of pregnancy in a woman with sickle cell disease. She underwent successful cesarean delivery of a healthy male fetus at 27 weeks with concurrent OLT. This report provides a literature review of OLT in pregnancy and examines the common causes of ALF in the pregnant patient. On the basis of the management and outcome of our case and the literature review, we present an algorithm for the suggested management of ALF in pregnancy. |
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Authors:
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Mara Greenberg; Tami J Daugherty; Arvand Elihu; Ravi Sharaf; Waldo Concepcion; Maurice Druzin; Carlos O Esquivel |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society Volume: 15 ISSN: 1527-6473 ISO Abbreviation: Liver Transpl. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-05 Completed Date: 2009-12-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100909185 Medline TA: Liver Transpl Country: United States |
Other Details:
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Languages: eng Pagination: 1236-41 Citation Subset: IM |
Copyright Information:
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Copyright 2009 AASLD |
Affiliation:
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Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford, CA 94304-1510, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms Anemia, Sickle Cell / complications*, diagnosis*, therapy Cesarean Section Female Humans Liver Failure, Acute / complications*, diagnosis*, therapy Male Polymerase Chain Reaction Pregnancy Pregnancy Complications Pregnancy Outcome Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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