| Acute limb deterioration during intra-arterial thrombolysis. | |
| | |
MedLine Citation:
|
PMID: 8402106 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Approximately 12 per cent of limbs undergoing intra-arterial thrombolysis (IAT) develop distal embolism or extension of thrombus during the procedure. These are usually of little clinical consequence and can be treated by increasing the rate of administration of the lytic agent. However, in some patients the clinical condition of the limb deteriorates rapidly. In an attempt to define the incidence of acute limb deterioration during IAT, information was collected from five centres in the UK with experience of the technique. A total of 866 treatments were recorded, with 20 limbs (2.3 per cent) undergoing acute deterioration. This complication was more common during the treatment of thrombosed popliteal aneurysm than during that of emboli or thrombosed atheromatous arteries or grafts (P < 0.001). The amputation rate associated with the complication was high, and operative intervention provided better results than continuation of lysis. |
| | |
Authors:
|
R B Galland; J J Earnshaw; R N Baird; R J Lonsdale; B R Hopkinson; A E Giddings; K J Dawson; G Hamilton |
Related Documents
:
|
18215666 - Anesthetic efficacy of a repeated intraosseous injection following a primary intraosseo... 11898496 - New insights on thrombolytic treatment of acute ischemic stroke. 9351116 - Repeat intra-arterial papaverine for recurrent cerebral vasospasm after subarachnoid ha... 3631116 - Role of thrombolysis in peripheral arterial occlusion. 12715116 - Intrarenal artery injection of l-arginine inhibits spontaneous activity of renal affere... 9712566 - Doppler estimation of portal blood flow after percutaneous transhepatic portal vein emb... |
Publication Detail:
|
Type: Journal Article; Multicenter Study |
Journal Detail:
|
Title: The British journal of surgery Volume: 80 ISSN: 0007-1323 ISO Abbreviation: Br J Surg Publication Date: 1993 Sep |
Date Detail:
|
Created Date: 1993-11-22 Completed Date: 1993-11-22 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0372553 Medline TA: Br J Surg Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 1118-20 Citation Subset: AIM; IM |
Affiliation:
|
Department of Surgery, Royal Berkshire Hospital, Reading, UK. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aneurysm
/
complications Humans Ischemia / chemically induced* Leg / blood supply Popliteal Artery Prognosis Recurrence Thrombolytic Therapy / adverse effects* Vascular Patency |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Idiopathic slow-transit constipation.
Next Document: Abdominal aortic aneurysm in the elderly.