| Acute leukemia during pregnancy. Association with immune-mediated thrombocytopenia in mother and infant. | |
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MedLine Citation:
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PMID: 1691571 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A 29-year-old female in the 20th week of pregnancy was admitted because of a change in the ABO blood group and bleeding tendency. Acute myelogenous leukemia was diagnosed with a weak reaction of red blood cells with anti-A antibody and a decreased level of A-transferase activity. Though the patient tolerated intensive chemotherapy and achieved complete remission, thrombocytopenia persisted after consolidation chemotherapy. Since platelet-associated IgG was elevated, thrombocytopenia was considered to be immune-mediated. In the third trimester, premature separation of the normally implanted placenta developed and cesarean section was performed. The male baby was also thrombocytopenic, but successfully treated with gamma-globulin. |
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Authors:
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H Gondo; Y Hamasaki; H Nakayama; T Kondo; J Mitsuuchi; Y Kawaga; S Taniguchi; M Harada; Y Niho |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta haematologica Volume: 83 ISSN: 0001-5792 ISO Abbreviation: Acta Haematol. Publication Date: 1990 |
Date Detail:
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Created Date: 1990-05-21 Completed Date: 1990-05-21 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0141053 Medline TA: Acta Haematol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 140-4 Citation Subset: IM |
Affiliation:
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Division of Internal Medicine, Sanshinkai Hara Hospital, Fukuoka, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Abruptio Placentae
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etiology Adult Cesarean Section Female Humans Infant, Newborn Leukemia, Myeloid, Acute / blood*, drug therapy Male Pregnancy Pregnancy Complications, Hematologic / etiology*, therapy Pregnancy Complications, Neoplastic / blood*, drug therapy Pregnancy Trimester, Third Thrombocytopenia / congenital, etiology*, therapy gamma-Globulins / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/gamma-Globulins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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