Document Detail

Acute lead poisoning in two users of illicit methamphetamine.
MedLine Citation:
PMID:  3599348     Owner:  NLM     Status:  MEDLINE    
Acute lead poisoning can present a difficult diagnostic dilemma, with symptoms that mimic those of hepatitis, nephritis, and encephalopathy. We report two cases in intravenous methamphetamine users who presented with abnormal liver function values, low hematocrit values, basophilic stippling of red blood cells, and elevated blood lead levels. Both patients excreted large amounts of lead in their urine after treatment with edetic acid, followed by resolution of their symptoms. Lead contamination was proved in one drug sample. Basophilic stippling of the red blood cells was the one key laboratory result that led to the definitive diagnosis in both cases.
J V Allcott; R A Barnhart; L A Mooney
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  JAMA     Volume:  258     ISSN:  0098-7484     ISO Abbreviation:  JAMA     Publication Date:    1987 Jul 24-31
Date Detail:
Created Date:  1987-08-07     Completed Date:  1987-08-07     Revised Date:  2014-09-17    
Medline Journal Info:
Nlm Unique ID:  7501160     Medline TA:  JAMA     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  510-1     Citation Subset:  AIM; IM    
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MeSH Terms
Drug Contamination*
Injections, Intravenous
Lead Poisoning / diagnosis,  etiology*
Methamphetamine* / analysis
Street Drugs* / analysis
Substance-Related Disorders / complications*
Reg. No./Substance:
0/Street Drugs; 44RAL3456C/Methamphetamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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