Document Detail

Acute laryngotracheobronchitis and associated transient hyperphosphatasemia: a new case of transient hyperphosphatasemia in early childhood.
MedLine Citation:
PMID:  16509919     Owner:  NLM     Status:  MEDLINE    
We report the case of a 20-month old boy with markedly elevated serum alkaline phosphatase (ALP) levels, documented during an episode of acute laryngotracheobronchitis. Biochemical investigations and imaging studies revealed no evidence of bone or liver disease. Transient hyperphosphatasemia (TH) was confirmed when serum ALP levels normalized within 2 months. Several theories were suggested for TH pathophysiology, viral infections among them; the exact causes, however, remain unclear. It is important to recognize TH and avoid misdiagnosis and unnecessary investigations.
Maria Eboriadou; Georgia Skouli; Paraskevi Panagopoulou; Katerina Haidopoulou; Artemis Makedou; George Varlamis
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of paediatrics and child health     Volume:  42     ISSN:  1034-4810     ISO Abbreviation:  J Paediatr Child Health     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-03-02     Completed Date:  2007-02-16     Revised Date:  2007-09-24    
Medline Journal Info:
Nlm Unique ID:  9005421     Medline TA:  J Paediatr Child Health     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  149-50     Citation Subset:  IM    
4th Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Greece.
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MeSH Terms
Alkaline Phosphatase / blood*
Budesonide / administration & dosage
Croup / complications*,  drug therapy
Glucocorticoids / administration & dosage
Isoenzymes / blood
Methylprednisolone / administration & dosage
Nebulizers and Vaporizers
Phosphorus Metabolism Disorders / diagnosis*,  drug therapy,  metabolism
Treatment Outcome
Reg. No./Substance:
0/Glucocorticoids; 0/Isoenzymes; 51333-22-3/Budesonide; 83-43-2/Methylprednisolone; EC Phosphatase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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