Document Detail


[Acute kidney injury secondary to steroid-induced tumor lysis in an adolescent with acute lymphoblastic leukemia: Role of urinary alkalinisation and peritoneal dialysis].
MedLine Citation:
PMID:  23224315     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
An adolescent with acute lymphoblastic leukemia developed an early and severe tumor lysis syndrome with acute kidney injury after a low and single dose of steroids. Renal dysfunction was attributed primarily to phosphate nephropathy with nephrocalcinosis due to extreme elevations of phosphate in blood. Urinary alkalinization probably contributed to this development. We used peritoneal dialysis with resolution of nephrocalcinosis and normalization of creatinine clearance.
Authors:
Gustavo Roberto Marín; Elena Majek
Publication Detail:
Type:  English Abstract; Journal Article    
Journal Detail:
Title:  Archivos argentinos de pediatría     Volume:  110     ISSN:  1668-3501     ISO Abbreviation:  Arch Argent Pediatr     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2012-12-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0372460     Medline TA:  Arch Argent Pediatr     Country:  Argentina    
Other Details:
Languages:  spa     Pagination:  e118-22     Citation Subset:  IM    
Affiliation:
Unidad de Nefrología, Hospital de Niños Héctor Quintana.
Vernacular Title:
Lesión renal aguda secundaria a lisis tumoral inducida por esteroides en una adolescente con leucemia linfoblástica aguda: Rol de la alcalinización urinaria y diálisis peritoneal.
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