| Acute kidney injury in the pregnant patient. | |
| | |
MedLine Citation:
|
PMID: 23164415 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Acute kidney injury (AKI) is costly and is associated with increased mortality and morbidity. An understanding of the renal physiologic changes that occur during pregnancy is essential for proper evaluation, diagnosis, and management of AKI. As in the general population, AKI can occur from prerenal, intrinsic, and post-renal causes. Major causes of pre-renal azotemia include hyperemesis gravidarum and uterine hemorrhage in the setting of placental abruption. Intrinsic etiologies include infections from acute pyelonephritis and septic abortion, bilateral cortical necrosis, and acute tubular necrosis. Particular attention should be paid to specific conditions that lead to AKI during the second and third trimesters, such as preeclampsia, HELLP syndrome, acute fatty liver of pregnancy, and TTP-HUS. For each of these disorders, delivery of the fetus is the recommended therapeutic option, with additional therapies indicated for each specific disease entity. An understanding of the various etiologies of AKI in the pregnant patient is key to the appropriate clinical management, prevention of adverse maternal outcomes, and safe delivery of the fetus. In pregnant women with pre-existing kidney disease, the degree of renal dysfunction is the major determining factor of pregnancy outcomes, which may further be complicated by a prior history of hypertension. |
| | |
Authors:
|
Rosemary Nwoko; Darko Plecas; Vesna D Garovic |
Related Documents
:
|
16916025 - Variations of chemical compositions in coarse aerosols and fine aerosols in two success... 22954075 - Comparison of perception of pregnancy risk of nulliparous women of advanced maternal ag... 17053895 - The pharmacokinetics of artemether and lumefantrine in pregnant women with uncomplicate... 19461965 - Recrudescent plasmodium berghei from pregnant mice displays enhanced binding to the pla... 11038405 - Equine uteroplacental metabolism at mid- and late gestation. 17615445 - Premature capacitation of frozen-thawed spermatozoa from subfertile japanese black cattle. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical nephrology Volume: 78 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 2012 Dec |
Date Detail:
|
Created Date: 2012-11-20 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: Germany |
Other Details:
|
Languages: eng Pagination: 478-86 Citation Subset: IM |
Affiliation:
|
Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN USA, and University Hospital for Obstetrics and Gynecology, School of Medicine, University of Belgrade, Serbia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clinical and pathological analysis of hepatitis B virus-related membranous nephropathy and idiopathi...
Next Document: Development of Wernicke's encephalopathy during initiation of hemodialysis in an elderly non-alcohol...