Document Detail

Acute kidney dysfunction secondary to the abdominal compartment syndrome.
MedLine Citation:
PMID:  17136682     Owner:  NLM     Status:  MEDLINE    
The abdominal compartment syndrome (ACS) occurs most commonly in the setting of major trauma and complex abdominal surgical procedures. The syndrome reflects the adverse physiological consequences of an acute increase in intra-abdominal pressure (generally >18 mm Hg). The effects of increased abdominal pressures on the kidney were initially described in 1876 and include impairment of renal blood flow and glomerular filtration resulting in oliguria or anuria and acute kidney dysfunction. These effects are magnified by the concomitant effects of increased intra-abdominal pressure to impair venous return and cardiac output. Patients with intra-abdominal hypertension (IAH) can be easily detected using simple methodology. If employed early, abdominal decompression to lower IAH is associated with restoration of organ function and avoidance of the ACS. However, the overall mortality associated with this syndrome remains high. In postsurgical, trauma patients, or those at risk, ACS should be considered as a potential etiology for acute kidney dysfunction and intra-abdominal pressures should be measured, monitored and when necessary intervened upon in order to attempt to improve organ dysfunction.
William Shear; Mitchell H Rosner
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of nephrology     Volume:  19     ISSN:  1121-8428     ISO Abbreviation:  J. Nephrol.     Publication Date:    2006 Sep-Oct
Date Detail:
Created Date:  2006-11-30     Completed Date:  2008-06-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9012268     Medline TA:  J Nephrol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  556-65     Citation Subset:  IM    
Department of Internal Medicine, University of Virginia Health System, Charlottesville, Virginia-USA.
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MeSH Terms
Abdominal Injuries / complications,  physiopathology*,  therapy
Anuria / etiology,  physiopathology
Cardiac Output
Glomerular Filtration Rate
Kidney Failure, Acute / etiology,  mortality,  physiopathology*,  therapy
Monitoring, Physiologic
Oliguria / etiology,  physiopathology
Renal Circulation

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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