| Acute ischaemia of the leg following accidental intra-arterial injection of dissolved flunitrazepam tablets. | |
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MedLine Citation:
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PMID: 19003750 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Accidental intra-arterial injection of drugs is a sporadic complication in i.v. drug addicts. A 22-year-old drug-abuser injected flunitrazepam tablets dissolved in tap water into her left femoral artery and presented with clinical signs of acute ischaemia of the left leg. Severe rhabdomyolysis developed within 5 hours after the injection. Selective arterial catheter angiography showed an acute occlusion of the posterior tibial artery. Combination therapy with i.a. urokinase, i.a. prostaglandines and i.v. anticoagulation resulted in re-opening of the obstructed distal artery and complete cessation of symptoms. |
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Authors:
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J A Leifert; L Bossaller; M Uhl |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: VASA. Zeitschrift für Gefässkrankheiten. Journal for vascular diseases Volume: 37 ISSN: 0301-1526 ISO Abbreviation: VASA Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-12 Completed Date: 2009-01-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0317051 Medline TA: Vasa Country: Switzerland |
Other Details:
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Languages: eng Pagination: 374-8 Citation Subset: IM |
Affiliation:
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Department Internal Medicine, University Hospital Freiburg, Germany. jens.leifert@uniklinik-freiburg.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Anticoagulants / therapeutic use Arterial Occlusive Diseases / chemically induced*, drug therapy, pathology Drug Therapy, Combination Female Femoral Artery Fibrinolytic Agents / therapeutic use Flunitrazepam / administration & dosage, adverse effects* GABA Modulators / administration & dosage, adverse effects* Humans Injections, Intra-Arterial Ischemia / chemically induced*, drug therapy, pathology Leg / blood supply* Prostaglandins / therapeutic use Rhabdomyolysis / chemically induced Solubility Substance Abuse, Intravenous / complications* Tablets Tibial Arteries / drug effects*, radiography Treatment Outcome Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Anticoagulants; 0/Fibrinolytic Agents; 0/GABA Modulators; 0/Prostaglandins; 0/Tablets; 1622-62-4/Flunitrazepam |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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