Document Detail

Acute intermittent porphyria associated with ovarian stimulation. A case report.
MedLine Citation:
PMID:  12698780     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Induction of ovulation in the course of infertility treatment is increasingly commonplace in the 21st century. As a consequence, it can be expected that previously unrecognized complications of the procedure will be reported. CASE: A 36-year-old woman presented with severe pelvic pain and hyponatremia after ovarian stimulation with gonadotropins. After admission with a presumptive diagnosis of ovarian hyperstimulation syndrome, a further family history revealed acute intermittent porphyria. A 24-hour urine collection confirmed the diagnosis. CONCLUSION: Hormonal therapy for induction of ovulation in the course of infertility treatment may precipitate attacks of acute intermittent porphyria. A careful history must be undertaken prior to administration of such hormonal preparations.
William B Seiden; Leo P Kelly; Rafi Ali
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  48     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  2003 Mar 
Date Detail:
Created Date:  2003-04-17     Completed Date:  2003-07-02     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  201-3     Citation Subset:  IM    
Department of Internal Medicine, Advocate Medical Group, Nesset Pavilion, 1775 West Ballard Road, Park Ridge, IL 60068, USA.
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MeSH Terms
Follicle Stimulating Hormone / adverse effects*
Hormones / adverse effects*
Ovulation Induction / adverse effects*
Porphyria, Acute Intermittent / chemically induced*,  diagnosis,  therapy
Reg. No./Substance:
0/Hormones; 9002-68-0/Follicle Stimulating Hormone

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