Document Detail

Acute hypoxic ventilatory response and exercise-induced arterial hypoxemia in men and women.
MedLine Citation:
PMID:  15477171     Owner:  NLM     Status:  MEDLINE    
Recent studies claim a higher prevalence of exercise-induced arterial hypoxemia (EIAH) in women relative to men and that diminished peripheral chemosensitivity is related to the degree of arterial desaturation during exercise in male endurance athletes. The purpose of this study was to determine the relationship between the acute ventilatory response to hypoxia (AHVR) and EIAH and the potential influence of gender in trained endurance cyclists and untrained individuals. Healthy untrained males (n = 9) and females (n = 9) and trained male (n = 11) and female (n = 10) cyclists performed an isocapnic AHVR test followed by an incremental cycle test to exhaustion. Oxyhemoglobin saturation (Sa(O(2)) was lower in trained men (91.4 +/- 0.9%) and women (91.3 +/- 0.9%) compared to their untrained counterparts (94.4 +/- 0.8% versus 94.3 +/- 0.7%) (P < 0.05). AHVR and maximal O(2) consumption were related for all subjects (r = -0.46), men (r = -0.45) and women (r = -0.53) (P < 0.05) but AHVR was unrelated to Sa(O(2)) for any groups (P > 0.05). We conclude that resting AHVR does not have a significant role in maintaining Sa(O(2)) during sea-level maximal cycle exercise in men or women.
Jordan A Guenette; Tu T Diep; Michael S Koehle; Glen E Foster; Jennifer C Richards; A William Sheel
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Respiratory physiology & neurobiology     Volume:  143     ISSN:  1569-9048     ISO Abbreviation:  Respir Physiol Neurobiol     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-10-12     Completed Date:  2004-12-22     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  101140022     Medline TA:  Respir Physiol Neurobiol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  37-48     Citation Subset:  IM    
Health and Integrative Physiology Laboratory, School of Human Kinetics, The University of British Columbia, Vancouver, BC, Canada V6T 1Z1.
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MeSH Terms
Anoxia / physiopathology*
Exercise / physiology*
Exercise Test
Oxygen / blood
Oxygen Consumption / physiology
Physical Fitness / physiology*
Respiratory Function Tests
Respiratory Physiological Phenomena*
Sex Factors
Reg. No./Substance:

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