Document Detail

Acute hyperglycemia and spontaneous reperfusion in acute myocardial infarction.
MedLine Citation:
PMID:  19548129     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Spontaneous reperfusion (SR) may occur in patients with ST elevation myocardial infarction (STEMI) prior to reperfusion therapy. Hyperglycemia is common on admission in patients with STEMI and is associated with a worse prognosis. Mechanisms remain unclear but may include impairment of coronary flow. The objective of this study was to examine whether acute hyperglycemia influenced the occurrence of SR in patients with STEMI. METHODS: All patients presenting to our institution with acute STEMI with measurement of glucose levels on presentation were eligible. SR was defined as a combination of significant relief of chest pain associated with an at least 70% resolution of ST segment elevation on follow-up ECG. RESULTS: 465 patients were studied of whom 77 patients met criteria for SR. Average glucose levels were not significantly different between the SR and non-SR groups (10.0+/-5.6 mmol/l versus 10.1+/-5.3; P=NS). When patients were divided into normoglycemic and hyperglycemic groups, there was no significant difference in the percentages of such patients in the SR and non-SR groups. (52% versus 54%; P=NS). CONCLUSIONS: Acute hyperglycemia on admission does not predict the occurrence of SR in a general population of patients with acute MI.
David Leibowitz; Johannes Nowatzky; A Teddy Weiss; David Rott
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acute cardiac care     Volume:  11     ISSN:  1748-295X     ISO Abbreviation:  Acute Card Care     Publication Date:  2009  
Date Detail:
Created Date:  2010-06-14     Completed Date:  2010-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101276603     Medline TA:  Acute Card Care     Country:  England    
Other Details:
Languages:  eng     Pagination:  151-4     Citation Subset:  IM    
Coronary Care Unit, Hadassah-Hebrew University Medical Center, Mount Scopus, Jerusalem, Israel.
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MeSH Terms
Acute Disease
Coronary Circulation*
Electrocardiogram Pattern
Hyperglycemia / complications*,  therapy
Middle Aged
Myocardial Infarction / complications*,  physiopathology*,  therapy
Myocardial Reperfusion
Retrospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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