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Acute high-intensity interval exercise reduces the postprandial glucose response and prevalence of hyperglycemia in patients with type 2 diabetes.
MedLine Citation:
PMID:  22268455     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
High-volume endurance exercise (END) improves glycemic control in type 2 diabetes (T2D) but many individuals cite ''lack of time'' as a barrier to regular participation. High-intensity interval training (HIT) is a time-efficient method to induce physiological adaptations similar to END, but little is known regarding the effect of HIT in T2D. Using continuous glucose monitoring (CGM), we examined the 24-h blood glucose response to one session of HIT consisting of 10x60s cycling efforts at 90% maximal heart rate, interspersed with 60s rest. Seven adults with T2D underwent CGM for 24-h on two occasions under standard dietary conditions: following acute HIT and on a non-exercise control day (CTL). HIT reduced hyperglycemia measured as proportion of time spent above 10mmol/L (HIT: 4.5±4.4 vs. CTL: 15.2±12.3 %, p=0.04). Postprandial hyperglycemia, measured as the sum of post-meal areas under the glucose curve, was also lower after HIT vs. CTL (728±331 vs. 1142±556 mmol/L•9h, p=0.01). These findings highlight the potential for HIT to improve glycemic control in T2D.
Authors:
Jenna B Gillen; Jonathan P Little; Zubin Punthakee; Mark A Tarnopolsky; Michael C Riddell; Martin J Gibala
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-23
Journal Detail:
Title:  Diabetes, obesity & metabolism     Volume:  -     ISSN:  1463-1326     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883645     Medline TA:  Diabetes Obes Metab     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Blackwell Publishing Ltd.
Affiliation:
Department of Kinesiology, McMaster University, Hamilton, ON CANADA Departments of Pediatrics & Medicine, McMaster University, Hamilton, ON CANADA Department of Kinesiology and Health Science, York University, Hamilton, ON CANADA.
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