Document Detail

Acute hemodynamic effects of estrogen administration in postmenopausal women.
MedLine Citation:
PMID:  9285677     Owner:  NLM     Status:  MEDLINE    
The hemodynamic effects of estrogens in replacement doses have not been fully clarified; therefore, we studied the acute hemodynamic changes after 0.625 and 1.25 mg of conjugated estrogens, administered intravenously, using a thermodilution catheter, in postmenopausal women without structural heart disease. Pulmonary and systemic pressures and resistances and stroke volume did not change compared with baseline, but heart rate and cardiac output decreased significantly, which may be associated with estrogen's previously described calcium-blocking effect or with a more recently contemplated beta-blocking action.
E Sbarouni; Z S Kyriakides; A Antoniadis; D T Kremastinos
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The American journal of cardiology     Volume:  80     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1997-09-16     Completed Date:  1997-09-16     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  532-5     Citation Subset:  AIM; IM    
Second Department of Cardiology, Onassis Cardiac Surgery Center, Athens, Greece.
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MeSH Terms
Estrogen Replacement Therapy*
Estrogens / administration & dosage,  pharmacology*
Hemodynamics / drug effects*
Injections, Intravenous
Middle Aged
Reg. No./Substance:

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