Document Detail


Acute heart failure syndromes and coronary perfusion.
MedLine Citation:
PMID:  18582629     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute heart failure syndromes (AHFS), with a high post-discharge mortality and rehospitalization rate, represent a significant public health burden. The treatment of patients hospitalized with AHFS often includes the use of vasoactive medications such as inotropes and vasodilators. Although such agents are frequently used, their safety and efficacy remain controversial. A significant number of patients with heart failure have underlying coronary artery disease and may be at greater risk from hemodynamic alterations that can diminish coronary perfusion. In AHFS, the relationship among vasoactive medications, coronary perfusion, and potential myocardial injury needs further investigation. Newer techniques now available to evaluate coronary perfusion should provide guidance for the evaluation of existing and future vasoactive therapies for AHFS.
Authors:
Nirat Beohar; Ata K Erdogan; Daniel C Lee; Hani N Sabbah; Morton J Kern; John Teerlink; Robert O Bonow; Mihai Gheorghiade
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of the American College of Cardiology     Volume:  52     ISSN:  1558-3597     ISO Abbreviation:  J. Am. Coll. Cardiol.     Publication Date:  2008 Jul 
Date Detail:
Created Date:  2008-06-27     Completed Date:  2008-07-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8301365     Medline TA:  J Am Coll Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  13-6     Citation Subset:  AIM; IM    
Affiliation:
Bluhm Cardiovascular Institute, Feinberg School of Medicine, Northwestern Memorial Hospital, Chicago, Illinois 60611, USA. n-beohar@northwestern.edu
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Coronary Artery Disease / physiopathology*
Coronary Circulation*
Fractional Flow Reserve, Myocardial
Heart Failure / drug therapy,  physiopathology*
Hemodynamics
Humans
Microcirculation
Syndrome
Tomography, Emission-Computed, Single-Photon

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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