Document Detail


Acute haemodynamic effects of the beta 1-adrenoceptor partial agonist xamoterol at rest and during supine exercise in patients with left ventricular dysfunction due to ischaemic heart disease: a double-blind randomized trial.
MedLine Citation:
PMID:  1971590     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The effects of xamoterol 0.2 mg kg-1 i.v. and placebo on left ventricular function at rest and on exercise were compared in patients with left ventricular dysfunction due to ischaemic heart disease. Improvements were seen in systolic and diastolic function at rest, and at up to 50% of maximal exercise, without evidence of worsening myocardial ischaemia.
Authors:
P J de Feyter; P W Serruys
Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  European heart journal     Volume:  11 Suppl A     ISSN:  0195-668X     ISO Abbreviation:  Eur. Heart J.     Publication Date:  1990 Apr 
Date Detail:
Created Date:  1990-07-05     Completed Date:  1990-07-05     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8006263     Medline TA:  Eur Heart J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  48-9     Citation Subset:  IM    
Affiliation:
Thoraxcentre, Erasmus University, Rotterdam, The Netherlands.
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MeSH Terms
Descriptor/Qualifier:
Adrenergic beta-Agonists / pharmacology
Adult
Aged
Blood Pressure / drug effects*
Cardiac Output / drug effects*
Coronary Disease / physiopathology*
Double-Blind Method
Exercise / physiology*
Humans
Male
Middle Aged
Propanolamines / pharmacology*
Randomized Controlled Trials as Topic
Xamoterol
Chemical
Reg. No./Substance:
0/Adrenergic beta-Agonists; 0/Propanolamines; 81801-12-9/Xamoterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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