| Acute graft-versus-host disease with unusual cutaneous intracellular vacuolation in an infant with severe combined immunodeficiency. | |
MedLine Citation:
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PMID: 8747575 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report an infant with severe combined immunodeficiency (SCID) who had cutaneous manifestations of acute graft-versus-host disease (GVHD) due to maternofetal lymphocyte engraftment. Histologic and ultrastructural examinations of the skin revealed intracellular vacuoles resembling lipid droplets in the epidermis and dermis, which is not a recognized feature of acute GVHD or SCID. |
Authors:
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A Farrell; L Scerri; A Stevens; L G Millard |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Pediatric dermatology Volume: 12 ISSN: 0736-8046 ISO Abbreviation: Pediatr Dermatol Publication Date: 1995 Dec |
Date Detail:
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Created Date: 1996-09-17 Completed Date: 1996-09-17 Revised Date: 2009-03-03 |
Medline Journal Info:
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Nlm Unique ID: 8406799 Medline TA: Pediatr Dermatol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 311-3 Citation Subset: IM |
Affiliation:
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Department of Dermatology, University Hospital, Queen's Medical Centre, Nottingham, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Dermatitis, Exfoliative / complications, pathology Female Graft vs Host Disease / complications* Humans Infant Keratinocytes / ultrastructure* Lymphocytes / immunology Male Maternal-Fetal Exchange / immunology Pregnancy Severe Combined Immunodeficiency / complications* Skin Diseases / complications*, pathology Vacuoles / ultrastructure |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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