| Acute graft-versus-host disease in children: abdominal CT findings. | |
| | |
MedLine Citation:
|
PMID: 8633157 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To review the computed tomographic (CT) appearance of acute gastrointestinal graft-versus-host disease (GVHD) in children. MATERIALS AND METHODS: Sixteen abdominal CT scans obtained in 12 children with acute gastrointestinal GVHD who underwent allogeneic bone marrow transplantation (BMT) were compared with 16 CT scans obtained in autologous bone marrow recipients not at risk for GVHD (control group). Autopsy findings in six patients with GVHD were compared with CT findings. RESULTS: All CT scans in patients with GVHD showed an abnormally enhanced, thin mucosal layer of bowel wall involving fluid-filled, dilated, poorly opacified bowel loops from the duodenum to the rectum. This corresponded histologically to mucosal destruction and replacement by a thin layer of highly vascular granulation tissue. Bowel wall thickening was often absent. Infiltration of mesenteric fat was seen in 91% of patients The control group showed no similar abnormalities. CONCLUSION: Acute gastrointestinal GVHD characteristically appears on CT scans as multiple, diffuse, fluid-filled bowel loops with a thin, enhancing layer of bowel wall mucosa. Bowel wall thickening often is absent. |
| | |
Authors:
|
L F Donnelly; C L Morris |
Related Documents
:
|
16055697 - Small-bowel obstruction in a phantom model of ex vivo porcine intestine: comparison of ... 9225807 - Indium-111-leukocyte imaging: a case of peritonitis mimicking inflammatory bowel disease. 21971137 - Feasibility study of a unilateral rf array coil for mr-scintimammography. 12659337 - Multidetector-row helical ct enteroclysis. 23179877 - Computed tomography and magnetic resonance imaging. 8367057 - Primary spinal extradural hydatid disease: report of a case with magnetic resonance cha... |
Publication Detail:
|
Type: Comparative Study; Journal Article |
Journal Detail:
|
Title: Radiology Volume: 199 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1996 Apr |
Date Detail:
|
Created Date: 1996-06-28 Completed Date: 1996-06-28 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 265-8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Radiology, Children's Hospital Medical Center, Cincinnati, OH 45229, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Bone Marrow Transplantation / adverse effects Case-Control Studies Child Female Gastrointestinal Diseases / etiology, pathology, radiography* Graft vs Host Disease / pathology, radiography* Humans Intestinal Mucosa / pathology, radiography Intestines / pathology, radiography Male Retrospective Studies Tomography, X-Ray Computed |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clockwise whirlpool sign at color Doppler US: an objective and definite sign of midgut volvulus.
Next Document: Color Doppler twinkling artifact in hyperechoic regions.